Description

What Is GHRP-6?

GHRP-6 is a synthetic hexapeptide with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂, first developed by Bowers et al. in the early 1980s as part of a systematic investigation into peptide analogues of met-enkephalin that retained GH-releasing activity without opioid activity. It was the first synthetic GH secretagogue to be characterised and has since become the reference compound of the GHRP class.

GHRP-6’s receptor was originally called the growth hormone secretagogue receptor (GHSR), but due to subsequent discoveries, the hormone ghrelin is now considered the receptor’s natural endogenous ligand  and the receptor has been renamed the ghrelin receptor. This reclassification underscores the historical significance of GHRP-6: its characterisation directly preceded and enabled the discovery of ghrelin as the endogenous ligand for the receptor it was found to activate.

GHRPs are endowed with the ability to bind two different receptors that mediate their cytoprotective and other pharmacological properties  GHS-R1a and CD36. GHS-R1a mediates GH secretion, positive inotropic cardiac effects, and NPY neuron activation; CD36 binding activates prosurvival pathways including PI-3K/AKT1, reduces reactive oxygen species spillover, enhances antioxidant defences, reduces inflammation, and confers anti-fibrotic effects via PPARγ upregulation and TGF-β downregulation.

As a research compound, GHRP-6 UK is the most extensively published founding GHRP in the scientific literature, with decades of peer-reviewed research spanning GH axis biology, cardiovascular science, wound healing, anti-fibrotic pharmacology, neuropeptide biology, gastrointestinal motility, and drug discovery. It is the reference peptide against which all subsequent GHRPs  including GHRP-2, Ipamorelin, and Hexarelin  have been characterised.

GHRP 6 DOSAGE:

Growth Hormone-Releasing Peptide 6 10mg/vial

PACKAGE CONTENT

1 Box of 1 Vial

HOW TO USE GHRP-6 (Growth Hormone-Releasing Peptide 6)

The saturation dose is 1mcg/kg, normally the dose used is always 100mcg 3-5 times a day, in total 300-500mcg.