Description
WHAT IS MELANOTAN II PEPTIDE HORMONE:
Melanotan II is a synthetic analogue of alpha-melanocyte stimulating hormone (α-MSH). It is a cyclic heptapeptide that binds to melanocortin receptors MC1R through MC5R. Research has examined its binding profile across the melanocortin receptor subtypes and its role as a reference compound in receptor-signalling studies. Its cyclic structure gives it better stability than linear α-MSH, making it one of the most widely used compounds in melanocortin receptor research. Supplied as lyophilised powder, third-party tested, lab certificate published on this page.
MELANOTAN 2 DOSAGE:
Melanotan II Peptide Hormone 10mg/vial
HOW TO USE MELANOTAN 2 PEPTIDE:
Inject 300mcg once daily for 1 – 2 weeks then 500mcg twice weekly thereafter for maintenance.
It can cause nausea, so it is recommended to use lower dosages at first.
MELANOTAN II (Melanotan II Peptide Hormone) Specifications
| Product Specification | Details |
|---|---|
| Product Name | Melanotan II |
| Alternative Name | Melanotan 2 / MT2 |
| Strength | 10mg |
| Peptide Class | Cyclic lactam α-MSH (4–10) analogue |
| Form | Lyophilised powder |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| Molecular Formula | C₅₀H₆₉N₁₅O₉ |
| Molecular Weight | 1024.2 g/mol |
| CAS Number | 121062-08-6 |
| Research Target | Melanocortin receptors |
| Research Use | In-vitro laboratory research |
Melanotan II Structure
Melanotan II is distinguished from the native α-MSH fragment by structural modifications including a lactam bridge, D-phenylalanine substitution and norleucine substitution.
These modifications constrain the peptide’s structure and contribute to its stability and receptor activity, making MT2 a useful compound for experimental melanocortin research.
Melanotan II vs Melanotan I
| Feature | Melanotan II | Melanotan I / Afamelanotide |
| Peptide structure | Cyclic | Linear |
| α-MSH analogue | Yes | Yes |
| Receptor research | MC1R, MC3R, MC4R, MC5R | Greater MC1R preference |
| Research role | Broad melanocortin receptor research | Primarily MC1R-focused research |
| Structure | Cyclic lactam | Linear peptide analogue |
Laboratory Research Information
Melanotan II is supplied as a lyophilised peptide powder. Laboratory handling and storage should follow the manufacturer’s analytical documentation and applicable laboratory protocols.
The current product information specifies protection from light and temperature-controlled storage for maintaining peptide integrity.
Quality & Testing
For research procurement, analytical documentation such as a Certificate of Analysis can help researchers verify:
- Peptide identity
- Purity
- Batch information
- Analytical methodology
- Quantity
- Release specifications
Is Melanotan II Approved in the UK?
Melanotan II is not a licensed medicine in the United Kingdom. The MHRA has previously warned about unauthorised Melanotan products and reported suspected adverse drug reactions associated with Melanotan II products.
This product should therefore be presented strictly as an in-vitro research compound, rather than as a medicine, tanning treatment or product intended for administration to humans.
Frequently Asked Questions
What is Melanotan II?
Melanotan II is a synthetic cyclic heptapeptide analogue of α-MSH that has been studied extensively in melanocortin receptor research.
What does MT2 stand for?
MT2 is a common abbreviation for Melanotan II.
What is Melanotan II used for in research?
Melanotan II is used as a reference compound in laboratory studies investigating melanocortin receptors, receptor signalling and structure–activity relationships.
What is the strength of this product?
This product is supplied as a 10mg lyophilised peptide.
What is the CAS number for Melanotan II?
The CAS number listed for Melanotan II is 121062-08-6.
Is Melanotan II the same as Melanotan I?
No. Although both are α-MSH analogues, they have different structures and receptor activity profiles.
Is Melanotan II licensed for human use in the UK?
No. Melanotan II is not a licensed medicine in the UK.
Is this product intended for human use?
No. The product should be presented strictly for in-vitro laboratory research and not for human or veterinary administration.
Research Disclaimer
MELANOTAN II (Melanotan II Peptide Hormone) is supplied strictly for laboratory research purposes. It is not intended for human consumption, veterinary use, medical treatment, diagnosis, prevention or cure of any disease. This product has not been evaluated or authorised by the MHRA or FDA for human therapeutic use.







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